Type: Package
Title: Censored Data Imputation for Direct Modeling
Version: 0.1.2
Description: Impute the survival times for censored observations based on their conditional survival distributions derived from the Kaplan-Meier estimator. 'CondiS' can replace the censored observations with the best approximations from the statistical model, allowing for direct application of machine learning-based methods. When covariates are available, 'CondiS' is extended by incorporating the covariate information through machine learning-based regression modeling ('CondiS_X'), which can further improve the imputed survival time.
License: GPL-2
Encoding: UTF-8
Depends: R (≥ 3.6)
Imports: caret, survival, kernlab, purrr, tidyverse, survminer
NeedsCompilation: no
Suggests: rmarkdown, knitr
VignetteBuilder: knitr
RoxygenNote: 7.1.2
Packaged: 2022-04-17 02:48:46 UTC; YWang70
Author: Yizhuo Wang ORCID iD [aut, cre], Ziyi Li [aut], Xuelin Huang [aut], Christopher Flowers [ctb]
Maintainer: Yizhuo Wang <ywang70@mdanderson.org>
Repository: CRAN
Date/Publication: 2022-04-17 03:12:29 UTC

CondiS Function

Description

This function allows you to impute survival time.

Usage

CondiS(time, status, tmax)

Arguments

time

The follow up time for right-censored data.

status

The censoring indicator, normally 0=right censored, 1=event at time.

tmax

A self-defined time-of-interest point; if left undefined, then it is defaulted as the maximum follow up time.


CondiS-X Function

Description

This function allows you to improve the imputed survival time by incorporating covariate information.

Usage

CondiS_X(pred_time, status, covariates, method)

Arguments

pred_time

The imputed follow up time for right-censored data.

status

The censoring indicator, normally 0=right censored, 1=event at time.

covariates

The additional patient data that is presumably associated with the survival time.

method

Choose from 8 machine learning algorithms; the default is "glm".